The repositioning of anthelminthic drugs from the benzimidazole carbamate (BZ) group – popular dog dewormers such as fenbendazole (FZ), mebendazole (MBZ) and albendazole (ABZ) – into anticancer medicines has opened new avenues for cancer therapy. However, there is no evidence that fenbendazole or other BZ-class drugs cure cancer.
Anecdotal claims of the use of a dog dewormer for cancer have gained traction globally, including on social media platforms such as Facebook and TikTok. Some of these posts and videos, which claim that a cancer patient using the Joe Tippens Protocol has cured their disease, have received millions of views.
In the Joe Tippens Protocol, patients take 222 mg of fenbendazole granules or liquid suspension a day seven days a week with food. They also take CBD oil, vitamin E and curcumin. Tippens’ cancer went into remission after three months of following the protocol.
According to research published in the journal Science, the reason might be that the bacteria Neisseria caninum, which is contained in fenbendazole, is capable of changing tumour development by directly killing cancer cells and by reprogramming the microenvironment surrounding them. Tumours grow by sedating the immune system to create an immunosuppressive environment that favours their growth. N. caninum is able to reduce the concentration of two molecules that allow tumours to sedate the immune system: VEGF, which helps them develop blood vessels and deliver nutrients to the tumour; and PD-L1, which prevents tumour cells from being killed by T-cells. dewormer for cancer